Illudin analogs, uses thereof, and methods for synthesizing the same
AssigneeLantern Pharma Inc.
InventorsGregory J. Tobin, Shawn T. Blumberg, Andrey D. Malakhov, Varsin A. Archer
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Abstract
This invention provides illudin derivatives, intermediates, preparation methods, pharmaceutical compositions and uses thereof. Specific examples include novel synthetic routes to prepare illudin derivatives and an illudin derivative having a positive optical rotation, which has therapeutic value.
Claims13
A compound having a positive optical rotation angle and having the formula I.
A mixture or racemic mixture having compounds with the formulas (I) and (II).
A compound having the formula (III)
- wherein R1, R2 and R3 are independently (C1-C4) alkyl or methyl.
-14. (canceled)
(canceled)
(canceled)
A compound having a positive optical rotation angle and having the formula IV.
Dependencies are inferred from the claim text.