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AssigneeChengdu Ribocure Pharmatech Company Limited
InventorsXiangrong SONG, Yuquan WEI
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The present invention relates to the field of pharmaceutical preparations, in particular, to a mannose modified targeting nano-preparations, a composition for preparing nano-preparations, a targeting element, a targeting vector, a prepared targeting drug and a preparation method and the application thereof. The described nano-preparations with targeting function is composed of the targeting ligand mannose and its derivatives, nano-preparations and main drug components, and the described targeting material is linked with the spacer material, and then linked with the nano-preparations material to prepare the nano-preparations. The targeting nano-preparations in the present invention has good targetability of mannose receptor, can effectively bond with mannose receptor on target cell. Moreover, the preparation method has universality, can be used for synthesizing a variety of targeting nano-preparations, and is conducive to purification and characterization.
A targeting nano-preparations modified by mannose and its derivatives, wherein composing of targeting ligand mannose and its derivatives, nano-preparations and main drug components, which can be used for vaccine delivery, targeted cancer therapy, and treatment of arteriosclerosis and various inflammatory diseases.
A composition for preparing nano-preparations with targeting function, wherein the composition comprises targeting material and basic nano-preparation material, and the targeting material is mannose and/or mannose derivative.
A composition for preparing a targeting element, wherein the composition is composed of targeting material and spacer material, and the targeting material is mannose and/or mannose derivative.
Dependencies are inferred from the claim text.