Inflammatory cytokine production inhibitor

Abstract

Inflammatory cytokine production inhibitors containing a tomato extract as an active ingredient, which inhibit the production of the inflammatory cytokines TNF-α and IL-6 and can be applied to drugs effective against inflammatory diseases caused by overproduction of these inflammatory cytokines, such as rheumatoid arthritis, ulcerative colitis, Crohn's disease, and type 2 diabetes, as well as to foods and drinks such as health foods, wherein the tomato extract is a raw tomato extract that is a high-molecular-weight fraction having a molecular weight of 10,000 or higher obtained by molecular weight fractionation.

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