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AssigneeThe Catholic University of Korea Industry-Academic Cooperation Foundation
InventorsSung Won KIM, Jung Ho CHUN, Sun hwa PARK, Jung Yeon LIM, Mi Hyun LIM
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The present invention relates to a pharmaceutical composition for treating cartilage damage, the composition comprising nasal septum chondrocytes (NSCs) as an active ingredient, and a method for producing the NSCs into a spheroidal shape. The NSCs enable the expression of type II collagen which is a constituent component of cartilage, and SOX9 which is involved in chondrogenic differentiation, and an excellent cartilage treatment effect was shown as a result of administrating spheroidal NSCs to an animal model of cartilage damage, and thus the pharmaceutical composition and the method for producing the NSCs, according to the present invention, may be useful employed in the field of autologous chondrocyte implantation.
A method of treating cartilage damage, comprising administering a pharmaceutical composition comprising nasal septum chondrocytes (NSCs) as an active ingredient into a subject.
A method of producing NSCs for treating cartilage damage, comprising:
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Dependencies are inferred from the claim text.