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US 2021/0196716 A1Published application
Compositions and methods for treating eye disorders
AssigneeThe Regents of the University of Michigan
InventorsCagri Giray BESIRLI, Thomas WUBBEN
Life of this patent
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Abstract
Provided herein are compositions and methods for treating eye disorders. In particular, provided herein are neuroprotective compositions and methods for treating vision loss and related disorders.
Claims22
A method of activating PKM2 in the eye of a subject, comprising administering a PKM2 activator to the eye of a subject, wherein said administering activates PKM2 in the eye of said subject.
A method of treating an eye disorder, comprising:
- administering a PKM2 activator to the eye of a subject in need thereof, wherein said administering treats or reduces symptoms of an eye disorder in said subject.
12-24. (canceled)
A method of treating an eye disorder, comprising:
- replacing a gene encoding PKM2 with a gene encoding PKM1 in the eye of a subject in need thereof, wherein said replacing treats or reduces symptoms of an eye disorder in said subject.
28-36. (canceled)
Dependencies are inferred from the claim text.