Expandable valve prosthesis with sealing mechanism
AssigneesSorin Group Italia S.r.l., Mayo Foundation for Medical Education and Research
InventorsRakesh M. Suri, W. Andrew Ziarno, Eric Manasse
Life of this patent
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Abstract
A prosthetic heart valve includes at least one sealing member. The sealing member is adapted to conform to any surface irregularities found on the inner surface of the valve annulus, including any calcium deposits formed on the valve leaflets. The sealing member can be self-expanding or non-expanding. When deployed, the sealing member is adapted to create a blood tight seal between the prosthetic heart valve and the inner surface of the valve annulus thereby minimizing and/or eliminating perivalvular leakage at the implantation site.
Claims20
A method of using a heart valve prosthesis at a native heart valve site of a patient, the method comprising:
- delivering a heart valve prosthesis in a radially collapsed configuration to an implantation position at the native heart valve site, the heart valve prosthesis comprising a plurality of prosthetic leaflets coupled to an anchoring structure and at least one non-inflatable, outer sealing skirt coupled to and extending circumferentially about a portion of the anchoring structure such that the anchoring structure does not pass through a side wall of the at least one non-inflatable, outer sealing skirt;
- transitioning the heart valve prosthesis from the radially collapsed configuration to an expanded configuration at the implantation position such that the at least one non-inflatable, outer sealing skirt conforms to an inner surface of a native annulus at the native heart valve site to reduce paravalvular leakage;
- and
- permitting blood flow through the heart valve prosthesis upon opening of the plurality of prosthetic leaflets.
A method of using a heart valve prosthesis at a native heart valve site of a patient, the method comprising:
- delivering a heart valve prosthesis in a radially collapsed configuration to an implantation position at the native heart valve site, the heart valve prosthesis comprising an anchoring structure comprising an outflow portion adapted to be disposed adjacent to a Valsalva sinus of the patient and an inflow portion adapted to engage and secure the anchoring structure to the native heart valve site, a plurality of prosthetic leaflets coupled to the anchoring structure, and at least one non-inflatable, outer sealing skirt coupled to and extending circumferentially about at least a portion of that inflow portion of the anchoring structure and adapted to permit blood flow into a coronary ostia of the patient;
- transitioning the heart valve prosthesis from the radially collapsed configuration to an expanded configuration at the implantation position such that the at least one non-inflatable, outer sealing skirt conforms to an inner surface of a native annulus at the native heart valve site to reduce paravalvular leakage;
- and
- permitting blood flow through the heart valve prosthesis upon opening of the plurality of prosthetic leaflets.
Dependencies are inferred from the claim text.