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US 2021/0188919 A1Published application
Porcine circovirus type 3 immunogenic compositions and methods of making and using the same
AssigneeKansas State University Research Foundation
InventorBen Hause
Life of this patent
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Abstract
A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analyses suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
Claims20
A composition comprising:
- at least one porcine circovirus type 3 protein selected from the group consisting of ORF1, ORF2, and ORF3;
- and
- a veterinary-acceptable carrier selected from the group consisting of a solvent, a dispersion media, a coating, a stabilizing agent, a diluent, a preservative, an antimicrobial agent, an antifungal agent, an isotonic agent, an adsorption delaying agent, or any combination thereof.
A nucleic acid comprising a nucleotide sequence selected from the group consisting of:
- a) a nucleotide sequence selected from the group consisting of SEQ ID No. 1, SEQ ID No. 3, SEQ ID No. 5, SEQ ID No.7, SEQ ID No. 9, or one of their fragments;
- b) a nucleotide sequence of a specific fragment of a sequence such as defined in a);
- c) a homologous nucleotide sequence having at least 80% identity with a sequence such as defined in a) or b);
- d) a complementary nucleotide sequence or sequence of RNA corresponding to a sequence such as defined in a), b) or c);
- e) a nucleotide sequence modified by a sequence such as defined in a), b), c) or d);
- and
- f) a recombinant vector comprising a nucleotide sequence such as defined in a), b), c), d), or e);
- and
- a veterinary-acceptable carrier selected from the group consisting of a solvent, a dispersion media, a coating, a stabilizing agent, a diluent, a preservative, an antibacterial agent, an antifungal agent, an isotonic agent, an adsorption delaying agent, or any combination thereof.
6 more elements
A composition comprising:
- a chimeric nucleic acid molecule including a plasmid nucleotide sequence containing a portion of porcine circovirus type 1 nucleic acid and a portion of porcine circovirus type 3 nucleic acid;
- and
- a veterinary-acceptable carrier selected from the group consisting of a solvent, a dispersion media, a coating, a stabilizing agent, a diluent, a preservative, an antibacterial agent, an antifungal agent, an isotonic agent, an adsorption delaying agent, or any combination thereof.
Dependencies are inferred from the claim text.