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US 2021/0172967 A1Published application
Microscope slide processing systems, consumable stainer modules, and methods of using the same
AssigneeVentana Medical Systems, Inc.
InventorsStefano Begolo, Leanna M. Levine
Life of this patent
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Abstract
Systems and methods that enable automated processing of specimens carried on microscope slides are described herein. Aspects of the technology are directed, for example, to automated specimen processing systems configured to use microfluidic slide processing modules to robotically process tissue specimens. The slide processing modules can include reagents and a flow cell with a reaction chamber for holding the tissue specimens and reagent.
Claims30
An automated staining system, comprising:
- a consumable microfluidic slide processing module configured to be installed in a staining instrument and including a plurality of reagent elements, and a flow cell connected to the plurality of reagent elements and including
- a slide-receiving region dimensioned to receive a microscope slide, and
- a cover having a gasket positioned to sealingly contact a specimen-bearing surface of the microscope slide to define a reaction chamber that is between the cover and the specimen-bearing surface and surrounded by the gasket, and wherein when the consumable microfluidic slide processing module is installed in the staining instrument, the staining instrument is operable to cause reagent from a reagent reservoir at a respective one of the reagent elements to be delivered to the reaction chamber.
A microfluidic slide processing module, comprising:
- a plurality of reagent elements;
- and
- a flow cell connected to the plurality of reagent elements, the flow cell including
- a slide-receiving region dimensioned to receive a microscope slide, and
- a cover having a gasket that contacts a specimen-bearing surface of the microscope slide to define a reaction chamber between the cover and the specimen-bearing surface, wherein the flow cell is configured to receive reagent from each one of the reagent elements and to deliver the received reagent to the reaction chamber.
2 more elements
30-36. (canceled)
Dependencies are inferred from the claim text.