Kit for measuring anti-cyclic citrullinated peptide antibody, application thereof, and test method

Abstract

A kit for measuring an anti-cyclic citrullinated peptide antibody, an application thereof, and a test method is provided. The kit includes a biotinylated antigen formed by coupling a plurality of branched peptide units having branched peptide chains using lysine, and the branched peptide units each is formed by coupling a plurality of citrullinated peptides using lysine. The kit and method have high test sensitivity and good specificity; compared with a mixed antigen, citrulline being coupled and then used as a single-component antigen, reduces the complexity of components of the antigen and the difficulty of quality control of the reagent, and improves inter-batch consistency, and quantitative test can be performed and the time needed to complete all procedures to obtain a result is 45 min.

Dependencies are inferred from the claim text.