Screen printing tissue models
AssigneesUniversity of Maryland, Baltimore County, University of Maryland, Baltimore
InventorsErin LAVIK, Steve BERNSTEIN, Adam DAY, Bryan IBARRA
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Abstract
A process of simply, cheaply, and reproducibly creating complex tissue models using screen printing and the tissue model prepared using the screen printing process. These models areamenable to high throughput screening. They will allow the study of components of disease progression and can be used for screening therapies.
Claims11
A synthetic multilamellar tissue model comprising (i) a substrate, (ii) a foundation comprising at least one layer comprising a hydrogel, and (iii) at least one non-foundational layer comprising one or more of proteins, cells, additional hydrogel, additional hydrogel comprising an additional constituent, collagen, and any combination thereof, wherein the synthetic multilamellar tissue model comprises at least one pattern having resolution in a range from about 20 μm to about 500 μm.
Dependencies are inferred from the claim text.