Infection-related preterm birth diagnostic method
AssigneeThe University of Western Australia
InventorsJeffrey Keelan, Matthew Scott Payne
Life of this patent
Estimating the term…
Abstract
A method to determine if a pregnant woman is at risk of infection-associated spontaneous pre-term birth (sPTB), the method comprising the steps of: b) testing a sample of vaginal fluid for the presence of the following bacteria: iv) Ureaplasma parvum genotype SV3 and/or Ureaplasma parvum genotype SV6; v) Gardnerella vaginalis ; and vi) Lactobacillus iners wherein the presence of the bacteria indicates that the subject is at risk of sPTB.
Claims11
A method to determine if a pregnant woman is at risk of infection-associated spontaneous pre-term birth (sPTB), the method comprising the steps of:
- a) testing a sample of vaginal fluid for the presence of the following bacteria:
- i) Ureaplasma parvum genotype SV3 and/or Ureaplasma parvum genotype SV6;
- ii) Gardnerella vaginalis;
- and
- iii) Lactobacillus iners
- wherein the presence of the bacteria indicates that the subject is at risk of sPTB.
A method to determine if a pregnant woman would benefit from treatment to prevent infection-associated spontaneous pre-term birth (sPTB), the method comprising the steps of:
- a) testing a sample of vaginal fluid for the presence of the following bacteria:
- i) Ureaplasma parvum genotype SV3 and/or Ureaplasma parvum genotype SV6;
- ii) Gardnerella vaginalis;
- and
- iii) Lactobacillus iners
- wherein the presence of the bacteria indicates that the subject is at risk of a sPTB and therefore would benefit from treatment to prevent sPTB.
A method to treat a pregnant woman at risk of infection-associated spontaneous pre-term birth (sPTB), comprising the steps of:
- a) testing a sample of vaginal fluid for the presence of the following bacteria:
- i) Ureaplasma parvum genotype SV3 and/or Ureaplasma parvum genotype SV6;
- ii) Gardnerella vaginalis;
- and
- iii) Lactobacillus iners
- b) if the bacteria are present, giving the pregnant woman antibiotic therapy to eliminate the bacteria.
A method of reducing the risk of a pregnant woman having a infection-associated spontaneous pre-term birth (sPTB), comprising the steps of:
- a) testing a sample of vaginal fluid for the presence of the following bacteria:
- i) Ureaplasma parvum genotype SV3 and/or Ureaplasma parvum genotype SV6;
- ii) Gardnerella vaginalis;
- and
- iii) Lactobacillus iners
- b) if the bacteria are present, giving the pregnant woman antibiotic therapy to eliminate the bacteria and therefore reduce the risk of sPTB.
A kit to determine if a pregnant woman is at risk of infection-associated spontaneous pre-term birth (sPTB), the kit comprising:
- a) a means for testing a sample of vaginal fluid for the presence of the following bacteria:
- i) Ureaplasma parvum genotype SV3 and/or Ureaplasma parvum genotype SV6;
- ii) Gardnerella vaginalis;
- and
- iii) Lactobacillus iners
- b) instructions for use.
Dependencies are inferred from the claim text.