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US 2021/0171652 A1Published application
Fusion proteins and antibodies targeting human red blood cell antigens
AssigneeThe Trustees of the University of Pennsylvania
InventorsCarlos H. Villa, Vladimir R. Muzykantov, Donald L. Siegel, Colin Greineder
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Abstract
Compositions and methods are provided for loading cargoes onto red blood cells. Provided herein are novel antibodies, fragments, fusion proteins and other conjugates which specifically bind red blood cells via RHCE or Band 3.
Claims25
1-3. (canceled)
An antibody or fragment thereof which specifically binds an epitope on an erythrocyte without causing significant adverse alteration of membrane deformability.
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24-26. (canceled)
29-30. (canceled)
Dependencies are inferred from the claim text.