Method for examining therapeutic effect on cancer and composition for inducing immune response
AssigneeKawasaki Gakuen Educational Foundation
InventorsMikio OKA, Eiichi NAKAYAMA, Yoshihiro OHUE, Koji KUROSE
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AssigneeKawasaki Gakuen Educational Foundation
InventorsMikio OKA, Eiichi NAKAYAMA, Yoshihiro OHUE, Koji KUROSE
Estimating the term…
[Object] To provide a novel examination method for a cancer treatment effect, screening method fora peptide fora cancer vaccine, and peptide and composition for inducing an immune response against cancer. [Solving Means] Provided are an examination method for a cancer treatment effect and a screening method for a peptide for a cancer vaccine each including detecting an antibody against a cancer/testis antigen or an anti-p53 antibody in a sample. It is suitable that an anti-XAGE1 antibody (IgG and/or IgA) be detected, or an anti-NY-ESO-1 antibody (IgG) be detected. Also provided are a novel peptide and novel composition for inducing immune responses against cancer.
An examination method for cancer treatment effect, comprising detecting antibodies against cancer/testis antigens in clinical samples.
An examination method for cancer treatment effects, comprising detecting anti-p53 antibody in clinical samples.
A reagent kit for examining cancer treatment effect, comprising:
At least one peptide selected from the group consisting of the following items a) to f):
A screening method for a peptide for a cancer vaccine, comprising detecting antibodies against cancer/testis antigens or an anti-p53 antibody in clinical samples.
A method of preparing activated CD4-positive T-cells or activated CD8-positive T-cells, comprising a step of subjecting CD4-positive T-cells or CD8-positive T-cells obtained from peripheral blood to stimulated culture with SLP1 having an amino acid sequence set forth in SEQ ID NO:
Dependencies are inferred from the claim text.