Workstation for Automated Control of an In Vitro System

Abstract

Provided are automated cell culture systems and related in vitro cell culture methods, including for a co-culture of different cell populations having different cell culture conditions. For example, the system may comprise a bioreactor having a plurality of cell culture compartments, the bioreactor having a fluid port fluidly connected to the plurality of cell culture compartments. A pump fluidly connected to the fluid port can provide a cell culture medium to the plurality of culture compartments. A sensor is operably connected to at least one of the plurality of cell culture compartments for measuring at least one cell culture parameter. In this manner, a controller electronically connected the pump and sensor, is configured to automatically adjust a pump flow rate and/or a cell culture gas content to provide a desired steady-state cell culture parameter for facilitating cells interactions and collection of products representative of said interactions.

Dependencies are inferred from the claim text.