Monoclonal antibody and use thereof
AssigneeSchool Juridical Person Kitasato Institute
InventorsTakashi FUKUYAMA, Hitoshi YAMAZAKI, Mariko OGI, Noritada KOBAYASHI, Yoshinobu ICHIKI, Masahiko HATAKEYAMA
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AssigneeSchool Juridical Person Kitasato Institute
InventorsTakashi FUKUYAMA, Hitoshi YAMAZAKI, Mariko OGI, Noritada KOBAYASHI, Yoshinobu ICHIKI, Masahiko HATAKEYAMA
Estimating the term…
Provided is a monoclonal antibody or a fragment thereof in which heavy-chain complementarity-determining regions (CDRs) 1 to 3 respectively consist of amino acid sequences of SEQ ID NOs: 2 to 4 and light-chain CDRs 1 to 3 respectively consist of amino acid sequences of SEQ ID NOs: 5 to 7; a monoclonal antibody or a fragment thereof in which heavy-chain CDRs 1 to 3 respectively consist of amino acid sequences obtained by deleting, substituting, or adding one or several amino acids in the amino acid sequences of SEQ ID NOs: 2 to 4 and light-chain CDRs 1 to 3 respectively consist of amino acid sequences obtained by deleting, substituting, or adding one or several amino acids in the amino acid sequences of SEQ ID NOs: 5 to 7, and which has binding properties to a KK-LC-1 protein; or a monoclonal antibody or a fragment thereof which competes with the monoclonal antibody or a fragment thereof in which the heavy-chain CDRs 1 to 3 respectively consist of the amino acid sequences of SEQ ID NOs: 2 to 4 and the light-chain CDRs 1 to 3 respectively consist of the amino acid sequences of SEQ ID NOs: 5 to 7, and has binding properties to the KK-LC-1 protein.
A monoclonal antibody or a fragment thereof, which is one of the following (i) to (iii):
A hybridoma cell line having an accession number of NITE BP-02527.
A method for detecting a KK-LC-1 protein in a biological sample, comprising detecting a peptide consisting of an amino acid sequence set forth in SEQ ID NO:
Dependencies are inferred from the claim text.