Methods for the Treatment and Diagnosis of Alzheimer's Disease and Traumatic Brain Injuries
AssigneesInserm (Institut National De La Sante Et De La Recherche Medicale), Centre National de la Recherche Scientifique (CNRS), Universite Pierre Et Marie Curie (Paris 6)
InventorsThierry Leveillard, Jose-Alain Sahel, Hawa Camara
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Abstract
The invention relates to the use of HNRNPC-expressing vectors for preventing and/or treating a tauopathy, such as Alzheimer's disease. The invention relates to methods for detecting a risk of developing a tauopathy such Alzheimer's disease in a patient, comprising the step of detecting the level of HNRNPC in a biological sample obtained from said patient.
Claims7
An expression vector comprising a nucleic acid encoding heterogeneous nuclear ribonuclear protein C (HNRNPC).
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6-11. (canceled)
A method for predicting a risk of developing a tauopathy in a patient comprising the step of detecting the Nxnl2 v2/(v1+v2) expression ratio in a biological sample obtained from said patient.
Dependencies are inferred from the claim text.