Vaginal composition comprising a combination of estrogen and vitamin d
AssigneeChemo Research, S.L.
InventorsEnrico COLLI, David F. ARCHER
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Abstract
The invention relates to vaginal composition comprising a combination of estrogen and vitamin D or a vitamin D analog at a daily dosage delivery of (i) estrogen ranging from 1 μg to 100 μg estrogen of estradiol equivalent and (ii) vitamin D or analog ranging from 7.5 μg to 100 μg of vitamin D equivalent.
Claims18
A vaginal composition comprising, as the active ingredients, a combination consisting of estrogen and vitamin D or a vitamin D analog at a daily dosage delivery of (i) estrogen ranging from 1 μg to 10 μg estrogen of estradiol equivalent and (ii) vitamin D or analog ranging from 7.5 μg to 100 μg of vitamin D equivalent.
A method for treating vaginal atrophy in a subject, comprising providing to a vagina of the subject a combination of estrogen and vitamin D or vitamin D analog at a daily dosage delivery of (i) estrogen ranging from 1 μg to 10 μg estrogen of estradiol equivalent and (ii) vitamin D or analog ranging from 7.5 μg to 100 μg of vitamin D equivalent.
A method for treating vaginal atrophy in a subject, comprising providing to a vagina of the subject a combination of estradiol and calcitriol at a daily dosage delivery of (i) estradiol ranging from 1 μg to 10 μg and (ii) calcitriol ranging from 0.075 μg to 1 μg.
The method of claim 17, wherein the daily dosage delivery of estrogen ranges from 1 μg to 7.5 μg of estradiol equivalent.
Dependencies are inferred from the claim text.