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US 2021/0060031 A1Published application
Use of phosphoinositide 3-kinase inhibitors for treatment of vascular malformations
AssigneeMemorial Sloan Kettering Cancer Center
InventorsEulalia Baselga, Pau Castel, Jose Baselga
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Abstract
The present disclosure relates to methods of treating a vascular malformation in a subject expressing a gain-of-function mutation in a PIK3CA gene comprising administering, to the subject, an effective amount of an agent that inhibits phosphoinositide 3-kinase (“PI3K”).
Claims14
A method of treating a venous malformation in a subject in need thereof, comprising providing to the subject an effective amount of a compound having CAS Registry No. 371943-05-4 represented by the formula:
Dependencies are inferred from the claim text.