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AssigneeEnhancedbio Inc.
InventorsEun Kyung CHOI, Seong-Yun JEONG, Si Yeol SONG, Yun-Yong PARK, Seok Soon PARK, Eun Jin JU, Eun Jung KO
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The present invention relates to a biomarker composition for diagnosing radiation-resistant cancer comprising PMVK as an active ingredient and a method of diagnosing radiation-resistant cancer using the same, and when the PMVK is knocked down, it is confirmed that the survival rate of cancer cells decreases during radiation treatment, and based on this, the possibility as a factor related to radiation therapy resistance to cancer was suggested, and the PMVK can be used as a new target to enhance the effect of radiation therapy on human cancer cells.
A method for diagnosing radiation-resistant cancer, comprising:
3-12. (canceled)
A method for enhancing radiation sensitivity to cancer cells comprising a step of administering to a subject in need thereof a pharmaceutical composition comprising a phosphomevalonate kinase (PMVK) protein expression inhibitor or activity inhibitor as an active ingredient.
17-18. (canceled)
A method of screening a radiation sensitivity enhancer for cancer cells, the method comprises:
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Dependencies are inferred from the claim text.