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US 2021/0010033 A1Published application
Recombinant hvt vectors expressing multiple antigens of avian pathogens and uses thereof
AssigneeBoehringer Ingelheim Animal Health USA Inc.
InventorsMichel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz, Aemro Kassa
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Abstract
The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
Claims17
A recombinant herpesvirus of turkeys (HVT) vector comprising:
- a first heterologous polynucleotide encoding a first avian pathogen antigen;
- and
- a second heterologous polynucleotide encoding a second avian pathogen antigen,
- wherein the first and the second heterologous polynucleotides are linked by IRES or P2A.
1 more element
Dependencies are inferred from the claim text.