Systems, methods, and devices for self-digitization of samples
AssigneeUniversity of Washington
InventorsDaniel T. CHIU, Bryant S. Fujimoto, Jason E. Kreutz
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Abstract
Systems, methods, and devices for discretizing and analyzing fluidic samples are provided. In one aspect, a microfluidic array for discretizing a fluidic sample comprises one or more flow channels and a plurality of fluidic compartments in fluidic communication with the one or more flow channels. In another aspect, a system for discretizing and analyzing fluidic samples comprises a rotor assembly shaped to receive a microfluidic device.
Claims21
1-89. (canceled)
A microfluidic array for discretizing a fluidic sample, the array comprising:
- a proximal array portion comprising a fluid inlet port and a fluid outlet port;
- a distal array portion away from the proximal portion;
- one or more flow channels each comprising a length extending from the proximal array portion to the distal array portion, a proximal end in fluidic communication with the fluid inlet port, and a distal end in fluidic communication with the fluid outlet port;
- and
- a plurality of fluidic compartments in fluidic communication with the one or more flow channels,
- wherein at least one flow channel of the one or more flow channels comprises a change in cross-sectional dimension along the length of the at least one flow channel from the proximal end to the distal end.
A microfluidic device for discretizing a fluidic sample, the microfluidic device comprising:
- a body comprising a proximal body portion and a distal body portion, and
- a plurality of microfluidic arrays of claim 1 disposed in the body such that the one or more flow channels of the plurality of microfluidic arrays extend substantially parallel to each other from the proximal body portion to the distal body portion.
Dependencies are inferred from the claim text.