Signatures and determinants for distinguishing between a bacterial and viral infection and methods of use thereof
AssigneeMeMed Diagnostics Ltd.
InventorsEran EDEN, Kfir OVED
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AssigneeMeMed Diagnostics Ltd.
InventorsEran EDEN, Kfir OVED
Estimating the term…
The present invention provides methods of detecting infection using biomarkers. The methods disclosed herein include measuring the expression level of one or more polypeptide determinants in which the alteration of the expression level indicates infection of the patient. The methods provided herein are for distinguishing between bacterial infection, mixed infection, and/or viral infection. The methods disclosed herein may also further comprise measuring one or more non-polypeptide determinants. The present disclosure also provides methods for selection of a treatment regimen for the subject based on whether the subject is identified as having a bacterial or mixed infection, or a viral infection.
A kit for a detection assay for distinguishing between bacterial and viral infections, the kit comprising a detection agent which specifically measures the amount of IFI27 mRNA in a sample of a subject, wherein the kit comprises no more than 10 additional agents which specifically measure the amount of 10 additional genes, wherein said additional genes are differentially expressed in a statistically significant manner in subjects with a bacterial infection compared to subjects with a viral infection.
A method of treating an infection in a subject in need thereof comprising:
Dependencies are inferred from the claim text.