Reduction of interferences in immunoassays
AssigneeRoche Diagnostics Operations, Inc.
InventorsJohannes Polz, Thomas Mock, Barbara Upmeier, Toralf Zarnt
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AssigneeRoche Diagnostics Operations, Inc.
InventorsJohannes Polz, Thomas Mock, Barbara Upmeier, Toralf Zarnt
Estimating the term…
The present invention relates to a method for determining an analyte in a sample, comprising a) contacting said sample with at least a first and a second detector compound; b) determining the amount of complexes comprising at least one detector compound; and, c) determining said analyte in a sample based on the result of step b), wherein said first detector compound comprises a first binding moiety and a first label, and said second detector compound comprises a second binding moiety and a second label, and wherein the first label and the second label are non-identical. The present invention further relates to a kit for detecting an analyte in a sample, comprising at least a first and a second detector compound for said analyte, wherein said first detector compound comprises a first binding moiety and a first label, and said second detector compound comprises a second binding moiety and a second label, and wherein the first label and the second label are non-identical; and to a device for determining an analyte in a sample, comprising at least a first and a second detector compound for said analyte, wherein said first detector compound comprises a first binding moiety and a first label, and said second detector compound comprises a second binding moiety and a second label, and wherein the first label and the second label are non-identical; and means for determining at least one signal obtained from said first label and said second label; and to the use of a composition comprising at least a first and a second detector compound for detecting an analyte, wherein said first detector compound comprises a first binding moiety and a first label, and said second detector compound comprises a second binding moiety and a second label, and wherein the first label and the second label are non-identical.
A method for determining an analyte in a sample comprising
A kit for detecting an analyte in a sample comprising at least a first detector compound and a second detector compound for said analyte, wherein said first detector compound comprises a first binding moiety and a first label, and said second detector compound comprises a second binding moiety and a second label, and wherein the first label and the second label are non-identical.
A device for determining an analyte in a sample comprising at least a first detector compound and a second detector compound for said analyte, wherein said first detector compound comprises a first binding moiety and a first label, and said second detector compound comprises a second binding moiety and a second label, and wherein the first label and the second label are non-identical;
(canceled)
A method for improving the specificity of the detection of an analyte in an assay, comprising replacing from 10% to 90% of a first detector compound by a second detector compound having a non-identical label.
A method for identifying a sample comprising an interferent confounding determination of an analyte with a detector compound having a first label comprising
Dependencies are inferred from the claim text.