Photo-Activatable Aggregation-Induced Emission Probe with In-Situ Generation Capability, Preparation Method Therefor and Application Thereof

A method of preparing a photo-activatable aggregation-induced emission probe with in-situ generation capability, wherein the method comprises obtaining the photo-activatable aggregation-induced emission probe by reacting a compound of formula I with a compound of formula II;

• wherein:
• the structure of the photo-activatable aggregation-induced emission probe is as shown in formula III:
• the compound of formula I is a bis(2-(2-hydroxybenzylidene)amino) aryl disulfide compound, having a structure as shown in the following formula I:
• the compound of formula II is thiol, having a structure as shown in formula II:
• HS—R2(I);
• in formulas I and III, R and R1 are independently hydrogen, halogen, ester group, cyano group, nitro group, substituted or unsubstituted alkyl, alkoxy, alkylamino group, alkylthio group, aryl, heteroaryl, aryloxy, arylamino group, arylthio group, heteroaryloxy, heteroarylamino group, and heteroarylthio group;
• and
• R2 is a substituted or unsubstituted alkyl and aryl;
• the substituted alkyl is hydroxyl substituted, ester-group substituted or carboxyl substituted alkyl;
• the hydroxyl substituted alkyl is an alkyl on which hydrogen is replaced by a hydroxyl;
• the ester-group substituted alkyl is an alkyl on which carbon is replaced by an ester group;
• the carboxyl substituted alkyl is an alkyl on which carbon is replaced by a carboxyl;
• or the thiol is mercapto-containing amino acid or mercapto-containing polypeptide.