Back to results
US 2020/0399457 A1Published application
Enhancing Bond Strength Of Medical Devices
AssigneeBecton, Dickinson and Company
InventorsJianbin Zhang, Theresa Hermel-Davidock, Edward Bryan Coughlin, Tea Datashvili
Life of this patent
Estimating the term…
Abstract
Components of medical devices include polypropylene-poly(ethylene oxide) amphiphilic graft copolymers (PP-g-PEO) in their base polymer formulations. The base polymeric formulations comprise at least a polymer or co-polymer of propylene. These components are suitable for solvent-bonding with other components and enhance bond strength of the medical devices.
Claims20
A tubing for a medical device formed from a blend comprising:
- a base polymeric formulation comprising:
- polyethylene, polypropylene, or combinations thereof;
- and a thermoplastic elastomer (TPE) comprising a total polyethylene and/or polypropylene in an amount of at least 60 mol %;
- wherein the base polymeric formulation excludes free poly(ethylene oxide);
- and
- an additive comprising a polypropylene-poly(ethylene oxide) amphiphilic graft copolymer (PP-g-PEO copolymer), the PP-g-PEO copolymer being effective to enhance solvent bonding of the tubing to a connector.
3 more elements
A medical device comprising:
- a tubing comprising:
- a polymeric blend consisting of a base polymeric formulation consisting of polyethylene, polypropylene, a thermoplastic elastomer (TPE) comprising a total polyethylene and/or polypropylene in an amount of at least 60 mol %, or combinations thereof, and excluding free poly(ethylene oxide);
- and
- an additive comprising a polypropylene-poly(ethylene oxide) amphiphilic graft copolymer (PP-g-PEO copolymer) according to Formula (I):
- wherein R is hydrogen, alkyl, substituted alkyl, vinylic substituted alkyl, hydrocarbyl, substituted hydrocarbyl, or vinylic substituted hydrocarbyl group;
- the molar percentages of grafted maleic anhydride units, m, is in the range from 2 to 10 mole percent;
- the molar values of propylene units, n, is in the range from 98 to 90 mole percent, and p is in the range of 5 to 500 ethylene oxide units;
- wherein the PP-g-PEO copolymer is present in the blend in an amount in the range of 0.01 to 2.5% by weight of the blend;
- and
- a connector bonded to the tubing;
- wherein the PP-g-PEO copolymer is effective to enhance solvent bonding of the tubing to the connector.
8 more elements
A medical tubing manufactured by a process comprising:
- melting a polymeric base consisting of polyethylene, polypropylene, a thermoplastic elastomer (TPE) comprising a total polyethylene and/or polypropylene in an amount of at least 60 mol %, or combinations thereof, and excluding free poly(ethylene oxide) at a temperature in the range of 60° C. to 300° C. to form a melted polymeric base;
- adding an additive comprising a polypropylene-poly(ethylene oxide) amphiphilic graft copolymer (PP-g-PEO copolymer) to the melted polymeric base to form a blend the PP-g-PEO copolymer being present in the blend in an amount in the range of 0.01 to 2.5% by weight of the blend;
- mixing the blend for a time period in the range of 15 seconds to 90 seconds;
- and
- melt extruding the blend to form the tubing.
2 more elements
A method of making a medical device comprising:
- obtaining a polypropylene-poly(ethylene oxide) amphiphilic graft copolymer (PP-g-PEO);
- combining the PP-g-PEO with a base polymeric formulation comprising at least a polymer or co-polymer of ethylene or propylene and excluding free poly(ethylene oxide) to form a blend, the PP-g-PEO being present in the blend in an amount in the range of about 0.01 to about 5.0% by weight of the blend;
- forming a tubing from the blend;
- bonding the tubing to a connector in the presence of a solvent to form the medical device;
- wherein the PP-g-PEO is effective to enhance bonding of the tubing to a connector.
2 more elements
Dependencies are inferred from the claim text.