Bioconjugates of Antibodies and Fuctionalized Magnetic Nanoparticles

A Bioconjugate containing a nanoparticle of the core shell type and one or more antibodies immobilized thereon, wherein:

• said core contains a metal or alloy having soft magnetic properties and
• said shell contains one or more graphene layers, wherein the outermost layer is functionalized by one or more of the groups according to formula (I):
• wherein
• (Z)m represents a spacer selected from polyglycidol with m repeating units;
• m is an integer between 10 and 30;
• FG represents independent from each other a functional group selected from OH, COOH, COOR, and CO(NH)R;
• R represents C1-C4 alkyl;
• and
• n is an integer between 6 and 100.