Antibodies to risperidone haptens and use thereof
AssigneeJanssen Pharmaceutica NV
InventorsEric HRYHORENKO, Banumathi SANKARAN, Thomas R. DeCORY, Theresa TUBBS, Linda COLT, Maarten VLIEGEN, Pieter Rik HASPESLAGH
Life of this patent
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Abstract
Disclosed is an antibody which binds to risperidone, which can be used to detect risperidone in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of risperidone, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.
Claims21
1-25. (canceled)
An isolated antibody or a binding fragment thereof, which binds to risperidone and which is generating in response to a conjugate of a compound of Formula I and an immunogenic carrier,
- wherein:
- R1 is H, or OH;
- R2 is O(CH2)rNH2,
- or O(CH2)rNHC(O)(CH2)mCO2H;
- wherein:
- r is 1, 2, 3, 4, or 5;
- m is 1, 2, 3, 4, or 5;
- and
- n is 1, 2, 3, 4, or 5.
Dependencies are inferred from the claim text.