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US 2020/0399396 A1Published application
Anti-tip-1 antibodies and uses thereof
AssigneePhanes Therapeutics, Inc.
InventorsMinghan Wang, Hui Zou, Joshua Oaks
Life of this patent
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Abstract
Anti-TIP-1 antibodies and antigen-binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, methods of producing the antibodies, and methods of using the antibodies for treating or preventing diseases, such as cancer.
Claims23
An isolated monoclonal antibody or antigen-binding fragment thereof comprising a heavy chain complementarity determining region 1 (HCDR1), HCDR2, HCDR3, a light chain complementarity determining region 1 (LCDR1), LCDR2, and LCDR3, having the polypeptide sequence of:
- a. SEQ ID NOs:3, 4, 5, 6, 7, and 8, respectively;
- wherein the antibody or antigen-binding fragment thereof specifically binds TIP 1.
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Dependencies are inferred from the claim text.