Methods of treating alzheimer's disease
AssigneeGenentech, Inc.
InventorsWilliam Cho, Michel Friesenhahn, Robert Paul, Michael Ward
Life of this patent
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Abstract
Methods of treating Alzheimer's Disease (AD) in patients suffering from mild to moderate AD, including ApoE4 positive patients and patients suffering from mild AD are provided.
Claims20
A method of reducing the decline in functional or cognitive capacity in a patient diagnosed with early or mild to moderate Alzheimer's Disease (AD) comprising administering crenezumab to a patient suffering from early or mild to moderate AD.
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A method of treating early or mild to moderate AD without increasing the risk of an adverse event comprising administering crenezumab to a patient diagnosed with early or mild to moderate AD in an amount that is effective to treat the AD without increasing the risk of a treatment emergent adverse event, wherein the adverse event is selected from:
- (i) Amyloid-Related Imaging Abnormality-Edema (ARIA-E) and (ii) Amyloid-Related Imaging Abnormality-Hemorrhage (ARIA-H).
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Dependencies are inferred from the claim text.