pH RESPONSIVE MATERIALS FOR OPTICAL MONITORING OF WOUND STATUS
OwnerClemens GAMERITHinventor
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Abstract
The disclosed technology relates to materials for the detection of wounds, e.g., chronic wounds or infected wounds, including compositions, substrates, kits, dressing materials, and articles, and systems containing such compounds. The disclosed technology further relates to methods of using these compositions, kits and systems in the diagnosis and/or detection of chronic or infected wounds based measurement of pH. Additional disclosure relates to methods of characterizing wounds based on pH of wounds or wound fluids and using such information to treat, manage, and follow-up patients suffering from chronic or infected wounds.
Claims20
A pH responsive material, comprising;
- an anchor material;
- a linking moiety;
- and
- a pH responsive element.
A pH responsive material having the structure:
- wherein;
- A is cellulose or a cellulose polymer;
- and
- each R1 is independently H or one or more functionalized or non-functionalized GPTMS monomers or a combination thereof.
The pH responsive material of claim 26, wherein the cellulose or cellulose polymer is a cellulose particle sprayed, printed, or deposited on a solid phase of the medical or diagnostic device, the solid phase comprising a dressing, a wound dressing, a bandage, filter paper, or a test strip.
A method of making a pH responsive material comprising the steps of:
- dissolving a linking moiety in an acidic solution;
- immersing an anchor material in the acidic solution;
- drying the anchor material;
- and
- soaking the anchor material in a solution comprising a pH responsive element.
Dependencies are inferred from the claim text.