Fluid dosing system

Pipetting system (100) comprising at least one fluid dosing system (1) comprising:

• a dosing chamber (3) divided in a fluid-tight manner by means of a displaceable membrane (5) into:
• a) a dosing compartment (3a);
• and
• b) a working fluid compartment (3b) filled with a working fluid having a bulk modulus of at least 1 GPa;
• a first fluid port (3c) in fluidic communication with said dosing compartment (3a);
• a second fluid port (3d) in fluidic communication with said working fluid compartment (3b);
• an expansion reservoir (9) in fluidic communication with said fluid second port (3d) and filled with said working fluid;
• a bidirectional pump (7) in fluidic communication with said second port (3d) and said expansion reservoir (9) so as to be able to pump said working fluid bidirectionally between said working fluid compartment (3b) and said expansion reservoir (9);
• a flow sensor (13) arranged to measure flow of said working fluid based on displacement of at least part of said expansion reservoir (9).

Flow cytometry system comprising at least one fluid dosing system (1) comprising

• a dosing chamber (3) divided in a fluid-tight manner by means of a displaceable membrane (5) into:
• a) a dosing compartment (3a);
• and
• b) a working fluid compartment (3b) filled with a working fluid having a bulk modulus of at least 1 GPa;
• a first fluid port (3c) in fluidic communication with said dosing compartment (3a);
• a second fluid port (3d) in fluidic communication with said working fluid compartment (3b);
• an expansion reservoir (9) in fluidic communication with said fluid second port (3d) and filled with said working fluid;
• a bidirectional pump (7) in fluidic communication with said second port (3d) and said expansion reservoir (9) so as to be able to pump said working fluid bidirectionally between said working fluid compartment (3b) and said expansion reservoir (9);
• a flow sensor (13) arranged to measure flow of said working fluid based on displacement of at least part of said expansion reservoir (9).

Microfluidic chip comprising at least one fluid dosing system (1) comprising:

• a dosing chamber (3) divided in a fluid-tight manner by means of a displaceable membrane (5) into:
• a) a dosing compartment (3a);
• and
• b) a working fluid compartment (3b) filled with a working fluid having a bulk modulus of at least 1 GPa;
• a first fluid port (3c) in fluidic communication with said dosing compartment (3a);
• a second fluid port (3d) in fluidic communication with said working fluid compartment (3b);
• an expansion reservoir (9) in fluidic communication with said fluid second port (3d) and filled with said working fluid;
• a bidirectional pump (7) in fluidic communication with said second port (3d) and said expansion reservoir (9) so as to be able to pump said working fluid bidirectionally between said working fluid compartment (3b) and said expansion reservoir (9);
• a flow sensor (13) arranged to measure flow of said working fluid based on displacement of at least part of said expansion reservoir (9).