US 2020/0390973 A1 · PERSONALIZED CLOSED LOOP OPTIMIZATION SYSTEMS AND METHODS

Abstract

A medical device system and related methods of automatically adjusting control parameters of a medical device are disclosed. One method involves obtaining data pertaining to a physiological condition of a patient during operation of the medical device in accordance with the operating mode, determining a plurality of adjusted values for the control parameter based at least in part on the data, determining a respective cost associated with each respective adjusted value for the control parameter based at least in part on the data using a cost function, identifying, from among the plurality of adjusted values, an optimized value from among the plurality of adjusted values, wherein the optimized value has a minimum cost associated therewith from among the plurality of costs, and updating the control parameter at the medical device to the optimized value.

Claims20

Dependent claims

A method of automatically adjusting a control parameter for an operating mode of a medical device, the method comprising:

obtaining data pertaining to a physiological condition of a patient during operation of the medical device;
determining a plurality of adjusted values for the control parameter based at least in part on the data;
for each of the plurality of adjusted values for the control parameter, determining a respective cost associated with the respective adjusted value for the control parameter based at least in part on the data using a cost function, resulting in a plurality of costs associated with each of the plurality of adjusted values;
identifying, from among the plurality of adjusted values, an optimized value from among the plurality of adjusted values, wherein the optimized value has a minimum cost associated therewith from among the plurality of costs;
and
updating the control parameter at the medical device to the optimized value.

3 more elements

A method of automatically adjusting a control parameter for an operating mode of an infusion device regulating a glucose level of a patient, the method comprising:

obtaining patient data comprising sensed glucose measurement data and event log data during a period of operation of the infusion device in accordance with the operating mode;
determining a plurality of adjusted values for the control parameter based at least in part on the sensed glucose measurement data;
for each of the plurality of adjusted values for the control parameter:
determining a simulated glucose profile for the patient corresponding to the period of operation based on the event log data and the respective adjusted value for the control parameter;
and
determining a respective cost associated with the respective adjusted value for the control parameter based at least in part on the simulated glucose profile using an asymmetric cost function;
identifying, from among the plurality of adjusted values, an optimized value from among the plurality of adjusted values, wherein the optimized value has a minimum cost associated therewith from among a plurality of costs associated with the plurality of adjusted values according to the asymmetric cost function;
and
updating the control parameter at the infusion device to the optimized value, wherein subsequent operation of the infusion device utilizes the optimized value to generate dosage commands for delivering insulin to the patient.

6 more elements

Dependencies are inferred from the claim text.

Personalized closed loop optimization systems and methods

Life of this patent

Personalized closed loop optimization systems and methods

Life of this patent

Abstract

Claims20