Articles of poly(butylene succinate) and copolymers thereof
AssigneeTepha, Inc.
InventorsSimon F. Williams, Said Rizk, David P. Martin, Skander Limem, Kai Guo, Amit Ganatra, German Oswaldo Hohl Lopez
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AssigneeTepha, Inc.
InventorsSimon F. Williams, Said Rizk, David P. Martin, Skander Limem, Kai Guo, Amit Ganatra, German Oswaldo Hohl Lopez
Estimating the term…
Resorbable implants, coverings and receptacles comprising poly(butylene succinate) and copolymers thereof have been developed. The implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing molding, pultrusion or other melt or solvent processing method. The implants, or the fibers preset therein, may be oriented. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators. The coverings, receptacles and implants described herein, may be made from meshes, webs, lattices, non-wovens, films, fibers, foams, molded, pultruded, machined and 3D printed forms.
An article comprising a polymeric composition comprising a 1,4-butanediol unit and a succinic acid unit, wherein the implant is formed by melt processing, and wherein the weight average molecular weight of the polymeric composition increases during melt processing.
Dependencies are inferred from the claim text.