Tissue substitute materials and methods for tissue repair
AssigneeAcera Surgical, Inc.
InventorMatthew MacEwan
Life of this patent
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Abstract
Non-woven graft materials for use in specialized surgical procedures such as neurosurgical procedures, methods for making the non-woven graft materials, and methods for repairing tissue such as neurological tissue using the non-woven graft materials are disclosed. More particularly, disclosed are non-woven graft materials including at least two distinct fiber compositions composed of different polymeric materials, methods for making the non-woven graft materials and methods for repairing tissue in an individual in need thereof using the non-woven graft materials.
Claims40
1-20. (canceled)
A bioabsorbable non-woven graft material for facilitating regeneration of tissue, the bioabsorbable non-woven graft material comprising:
- a first electrospun non-woven fiber composition, wherein the first electrospun non-woven fiber composition comprises a first polymer comprising glycolic acid;
- and
- a second electrospun non-woven fiber composition, wherein the second electrospun non-woven fiber composition comprises a second polymer comprising caprolactone,
- wherein the first electrospun non-woven fiber composition and the second electrospun nonwoven fiber composition comprise different polymers,
- wherein the first electrospun non-woven fiber composition and the second electrospun non-woven fiber composition are commingled throughout the bioabsorbable non-woven graft material to create an architecture resembling a native extracellular matrix,
- wherein the bioabsorbable non-woven graft material is configured to be used in conjunction with one or more sutures for attaching the bioabsorbable non-woven graft material to the tissue, and wherein the bioabsorbable non-woven graft material is configured to facilitate regeneration of the tissue.
A bioabsorbable non-woven graft material for facilitating regeneration of tissue, the bioabsorbable non-woven graft material comprising:
- a first electrospun non-woven fiber composition, wherein the first electrospun non-woven fiber composition comprises a first polymer comprising polydioxanone;
- and
- a second electrospun non-woven fiber composition, wherein the second electrospun non-woven fiber composition comprises a second polymer,
- wherein the first electrospun non-woven fiber composition and the second electrospun nonwoven fiber composition comprise different polymers,
- wherein the first electrospun non-woven fiber composition and the second electrospun non-woven fiber composition are commingled throughout the bioabsorbable non-woven graft material to create an architecture resembling a native extracellular matrix,
- wherein the bioabsorbable non-woven graft material is configured to be attached to the tissue, and wherein the bioabsorbable non-woven graft material is configured to facilitate regeneration of the tissue.
A bioabsorbable non-woven graft material for facilitating regeneration of tissue, the bioabsorbable non-woven graft material comprising:
- a first electrospun non-woven fiber composition, wherein the first electrospun non-woven fiber composition comprises a first polymer comprising glycolic acid;
- and
- a second electrospun non-woven fiber composition, wherein the second electrospun non-woven fiber composition comprises a second polymer comprising caprolactone,
- wherein the first electrospun non-woven fiber composition and the second electrospun nonwoven fiber composition comprise different polymers,
- wherein the first electrospun non-woven fiber composition and the second electrospun non-woven fiber composition are commingled throughout the bioabsorbable non-woven graft material to create an architecture resembling a native extracellular matrix,
- wherein the bioabsorbable non-woven graft material is configured to be attached to the tissue, and wherein the bioabsorbable non-woven graft material is configured to facilitate regeneration of the tissue,
- wherein the bioabsorbable non-woven graft material comprises a suture pull-out strength, the suture pull-out strength ranging from 1 Newtons to about 5 Newtons of force required for a suture to be torn from bioabsorbable non-woven graft material.
Dependencies are inferred from the claim text.