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US 2020/0390782 A1Published application
Renal dysfunction improving drug comprising optical isomer of 1,4-benzothiazepine-1-oxide derivative
AssigneesAetas Pharma Co., Ltd., Noboru Kaneko
InventorNoboru Kaneko
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Abstract
The present invention addresses the problem of providing a pharmaceutical composition for treatment of a variety of conditions accompanied by renal dysfunction. Renal dysfunction is improved by a pharmaceutical composition that comprises an optical isomer of a 1,4-benzothiazepine-1-oxide derivative represented by general formula [II] wherein, R represents a hydrogen atom or a hydroxyl group, and “*” indicates being an optical isomer. or a pharmacologically acceptable salt thereof.
Claims8
1-13. (canceled)
A method of improving renal dysfunction comprising:
- a step of administering an effective dose of a pharmaceutical composition, which comprises an optical isomer of the 1,4-benzothiazepine-1-oxide derivative having the following formula [II] or a pharmaceutically acceptable salt thereof, to a subject with renal dysfunction:
- wherein R represents a hydrogen atom or a hydroxyl group, and “*” indicates the presence of optical isomers.
Dependencies are inferred from the claim text.