Compositions and methods of use of beta-hydroxy-beta-methylbutyrate (hmb) for enhancing recovery from soft tissue trauma
AssigneeMetabolic Technologies, Inc.
InventorsShawn Baier, Naji Abumrad, Emily Harris
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Abstract
The present invention provides a composition comprising HMB. Methods of administering HMB to an animal are also described. HMB is administered to enhance recovery from soft tissue trauma, including both acute and non-acute soft tissue trauma. Enhanced recovery includes reduced recovery time and enhanced soft tissue healing.
Claims40
A method of enhancing recovery from acute soft tissue injury, comprising administering to a non-human animal in need thereof a composition comprising from about 0.001 to 0.2 grams of β-hydroxy-β-methylbutyric acid (HMB) per kilogram of body weight, wherein the HMB further comprises HMB in its free acid form, its salt, its ester or its lactone, and wherein soft tissue is selected from the list consisting of tendons, and ligaments.
A method of reducing recovery time from acute soft tissue injury, comprising administering to a non-human animal in need thereof a composition comprising from about 0.001 to 0.2 grams of β-hydroxy-β-methylbutyric acid (HMB) per kilogram of body weight, wherein the HMB further comprises HMB in its free acid form, its salt, its ester or its lactone and wherein soft tissue is selected from the list consisting of tendons, and ligaments.
A method of improving healing from acute soft tissue injury, comprising administering to a non-human animal in need thereof a composition comprising from about 0.001 to 0.2 grams of β-hydroxy-β-methylbutyric acid (HMB) per kilogram of body weight, wherein the HMB further comprises HMB in its free acid form, its salt, its ester or its lactone and wherein soft tissue is selected from the list consisting of tendons, ligaments.
A method of reducing recovery time from surgery, comprising administering to a non-human animal about to undergo, undergoing or just having undergone surgery a composition comprising from about 0.001 to 0.2 grams of β-hydroxy-β-methylbutyric acid (HMB) per kilogram of body weight, wherein the HMB further comprises HMB in its free acid form, its salt, its ester or its lactone.
A method for enhancing recovery in a non-human animal surgical patient comprising administering to the patient a composition comprising from about 0.001 to 0.2 grams of β-hydroxy-β-methylbutyric acid (HMB) per kilogram of body weight, wherein administration of the composition begins prior to surgery, during surgery or post-surgery and wherein the HMB further comprises HMB in its free acid form, its salt, its ester or its lactone.
A method of expediting the repair or regeneration of soft tissue that has been subjected to acute injury comprising administering to a non-human animal in need thereof a composition comprising from about 0.5 to about 30 grams of β-hydroxy-β-methylbutyric acid (HMB), wherein the soft tissue is selected from the list consisting of tendons and ligaments and wherein the HMB further comprises HMB in its free acid form, its salt, its ester or its lactone.
Dependencies are inferred from the claim text.