Cell proliferation inhibitor and cancer treatment or prevention pharmaceutical composition including cell proliferation inhibitor
OwnerYoshiro NIITSUinventor
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Abstract
The present invention provides a drug that makes it possible to effectively inhibit cancer cell growth. In particular, the present invention provides: a cell growth inhibitor for cancers in which the RAS/RAF/MEK/ERK signaling cascade has been activated, the cell growth inhibitor combining a drug that inhibits GSTP1 and a drug that inhibits the RAS/RAF/MEK/ERK signaling cascade; and a cell growth inhibitor for cancers in which the RAS/RAF/MEK/ERK signaling cascade has been activated, the cell growth inhibitor including a drug that inhibits interaction between GSTP1 and CRAF.
Claims15
A cell growth inhibitor against a cancer in which a RAS/RAF/MEK/ERK signaling cascade is activated, the cell growth inhibitor comprising a combination of a GSTP1-inhibiting drug and a RAS/RAF/MEK/ERK signaling cascade-inhibiting drug.
A cell growth inhibitor against a cancer in which a RAS/RAF/MEK/ERK signaling cascade is activated, the cell growth inhibitor comprising a GSTP1-inhibiting drug to be administered in combination with a RAS/RAF/MEK/ERK signaling cascade-inhibiting drug.
A cell growth inhibitor against a cancer in which a RAS/RAF/MEK/ERK signaling cascade is activated, the cell growth inhibitor comprising a RAS/RAF/MEK/ERK signaling cascade-inhibiting drug to be administered in combination with a GSTP1-inhibiting drug.
A cell growth inhibitor against a cancer in which a RAS/RAF/MEK/ERK signaling cascade is activated, the cell growth inhibitor comprising a drug that inhibits interaction between GSTP1 and CRAF.
Dependencies are inferred from the claim text.