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US 2020/0368392 A1Published application
Cardiovascular Prostheses
AssigneeCorMatrix Cardiovascular, Inc.
InventorRobert G. Matheny
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Abstract
Cardiovascular prostheses for treating, reconstructing and replacing damaged or diseased cardiovascular tissue that are formed from a cellular extracellular matrix (ECM). The cardiovascular prostheses comprise mesh structures comprising poly(glycerol sebacate) (PGS) and various antibiotics.
Claims4
A prosthesis for treating damaged biological tissue, comprising:
- a mesh structure comprising a plurality of fibers comprising an extracellular matrix (ECM) composition comprising acellular ECM from a mammalian tissue source and at least one antibiotic selected from the group consisting of vancomycin and gentamicin,
- each of said plurality of fibers comprising an outer surface,
- said plurality of ECM fibers comprising a coating disposed on said outer surface, said coating comprising a composition comprising poly(glycerol sebacate) (PGS).
A prosthesis for treating damaged biological tissue, comprising:
- a mesh structure comprising a plurality of fibers comprising a composition comprising acellular ECM from a mammalian tissue source, poly(glycerol sebacate) (PGS) and at least one antibiotic selected from the group consisting of vancomycin and gentamicin.
Dependencies are inferred from the claim text.