Preventing cytokine release syndrome
AssigneeThe Johns Hopkins University
InventorsBert Vogelstein, Kenneth W. Kinzler, Nickolas Papadopoulos, Shibin Zhou, Verena Staedtke, Renyuan Bai, Gregory J. Riggins
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Abstract
This document relates to methods and materials for preventing cytokine release syndrome (CRS). For example, methods and materials for using one or more catecholamine inhibitors to prevent a mammal from developing CRS are provided.
Claims20
A method for preventing cytokine release in a mammal, wherein said method comprises administering a catecholamine inhibitor to a mammal identified as being at risk of developing cytokine release syndrome (CRS).
A method for inhibiting catecholamine synthesis and/or catecholamine secretion in a mammal, wherein said method comprises administering a catecholamine inhibitor to said mammal.
A method for preventing transplant rejection in a mammal, wherein said method comprises administering a catecholamine inhibitor to said mammal.
Dependencies are inferred from the claim text.