Compositions including il-18 and il-22 and their use in anti-viral therapies
AssigneeGeorgia State University Research Foundation, Inc.
InventorsAndrew T. Gewirtz, Benyue Zhang
Life of this patent
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Abstract
The present invention is directed to compositions including the cytokines IL-18 and IL-22 or biologically active fragments or variants thereof. In some embodiments, the compositions further include a pharmaceutically acceptable carrier. The compositions can farther include other interleukins such as IL-1β, and IL-1β can be used as a combination therapy with either IL-18 or IL-22 or biologically active fragments or variants thereof.
Claims17
-20. (canceled)
A method of treating a microbial infection, the method comprising administering to a patient in need thereof a therapeutically effective amount of a composition comprising an interleukin-18 (IL-18) or a biologically active fragment or variant thereof, an interleukin 22 (IL-22) or a biologically active fragment or variant thereof, and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.