Threonate compounds and methods of use thereof
AssigneeNeurocentria, Inc.
InventorsGuosong Liu, Fei Mao, Qifeng Sun
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AssigneeNeurocentria, Inc.
InventorsGuosong Liu, Fei Mao, Qifeng Sun
Estimating the term…
Provided herein is a method of using threonate to alter cellular physiology, such as neuronal physiology. A method of the present disclosure may include providing to a medium comprising a cell, a threonate-containing compound, or a precursor thereof, to increase the concentration of threonate in the medium, where the increased concentration of threonate is sufficient to increase the concentration of magnesium in the cell. Also provided is a method that includes administering a threonate-containing compound, or a precursor thereof, to an individual, to increase synaptic density in the brain and/or to treat a neurological disorder, e.g., cognitive impairment. The threonate-containing compound of the present disclosure does not include magnesium threonate.
A method of increasing brain synaptic density of an individual, comprising:
A method of increasing intracellular magnesium concentration, comprising:
A method of treating a neurological disorder in an individual, comprising:
-40. (canceled)
Dependencies are inferred from the claim text.