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US 2020/0367529 A1Published application
Storage stable mixtures
AssigneeDsm IP Assets B.V.
InventorsDominik Josef BRUNNER, Laure CLASADONTE, Martin Reto GADIENT, Roland SCHUEPFER
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Abstract
The present invention relates to improved formulations of propandiol mononitrate and derivatives thereof as well as to the production of such formulations.
Claims15
A storage stable mixture comprising
- (a1) at least 5 wt.-%, based on the total weight of the mixture, of a powderous formulation comprising
- (i) a compound of formula (I)
- wherein
- n is an integer from 1 to 15
- R1 is selected from the group consisting of H, C1-C6alkyl, phenyl, —OH, —NH2, —CN, —COOH, —O(C═O)R8, —NHC(═O)R8, SO2NHR8, and —ONO2, and
- R8 is C1-C6alkyl, phenyl, pyridyl such as preferably 2-pyridyl with the proviso that when n is >3 the hydrocarbon chain may be interrupted by —O— or —NH—, and
- (ii) silica, and
- (a2) at least 10 wt.-%, based on the total weight of the mixture, of at least one inorganic carbonate.
5 more elements
Use of an inorganic carbonate to enhance the retention of a compound of formula (I)
- wherein
- n is an integer from 1 to 15
- R1 is selected from the group consisting of H, C1-C6alkyl, phenyl, —OH, —NH2, —CN, —COOH, —O(C═O)R8, —NHC(═O)R8, SO2NHR8, and ONO2, and
- R8 is C1-C6alkyl, phenyl, pyridyl such as preferably 2-pyridyl with the proviso that when n is >3 the hydrocarbon chain may be interrupted by —O— or —NH—
- in a powderous formulation comprising (i) the compound according to formula (I) and (ii) silica.
2 more elements
A method of improving the retention of a compound of formula (I)
- wherein
- n is an integer from 1 to 15
- R1 is selected from the group consisting of H, C1-C6alkyl, phenyl, —OH, —NH2, —CN, —COOH, —O(C═O)R8, —NHC(═O)R8, SO2NHR8, and —ONO2, and
- R8 is C1-C6alkyl, phenyl, pyridyl such as preferably 2-pyridyl
- with the proviso that when n is >3 the hydrocarbon chain may be interrupted by —O— or —NH—
- in a powderous formulation comprising (i) the compound according to formula (I) and (ii) silica, said method comprising admixing the powderous formulation with an inorganic carbonate with the proviso that the weight-ratio of the inorganic carbonate to the powderous formulation is at least 1.
3 more elements
Dependencies are inferred from the claim text.