Pacap stabilized peptide

A peptide consisting of a sequence or modified sequence wherein, in the sequence represented by the following formula:

• (SEQ ID NO:
• 3)
• H-X1-D-G-I-F-T-D-X2-Y-X3-R-Y-R-X4-X5-X6-A-X7-X8-
• X9-Y-L-A-A-V-X10
• {where X1 is a neutral amino acid, X2 is a neutral amino acid, X3 is a neutral amino acid, X4 is a basic amino acid, X5 is a neutral amino acid or egTz, X6 is a non-polar amino acid, X7 is a non-polar amino acid, X8 is a basic amino acid, X9 is a basic amino acid and X10 is a neutral amino acid},
• the carboxy group of the aspartic acid residue at position 3 and/or position 8 is replaced with tetrazole, wherein the peptide binds to PAC1R, VPAC1R and VPACR2, and wherein the modified sequence is a sequence having a deletion or addition of one or more amino acids in the sequence of SEQ ID NO:
• 3.