Novel crystal form of acalabrutinib and preparation method and use thereof
AssigneeCrystal Pharmaceutical (Suzhou) Co., Ltd.
InventorsMinhua Chen, Yanfeng Zhang, Yuan Liu, Jianming Wang
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AssigneeCrystal Pharmaceutical (Suzhou) Co., Ltd.
InventorsMinhua Chen, Yanfeng Zhang, Yuan Liu, Jianming Wang
Estimating the term…
The present disclosure relates to novel crystalline forms of acalabrutinib and processes for preparation thereof. The present disclosure also relates to pharmaceutical compositions containing acalabrutinib, use of acalabrutinib for preparing Bruton's tyrosine kinase inhibitor drug, and use of acalabrutinib for preparing drugs treating mantle cell lymphoma. The crystalline forms of the present disclosure have one or more improved properties compared with prior art, and have significant value for future drug optimization and development.
An ethyl L-lactate solvate crystalline form A of acalabrutinib,
A glycerol solvate crystalline form D of acalabrutinib,
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Dependencies are inferred from the claim text.