Therapeutic use of compounds
AssigneeUCL Business PLC
InventorsRobin Simon Brooke Williams, Matthew Walker
Life of this patent
Estimating the term…
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AssigneeUCL Business PLC
InventorsRobin Simon Brooke Williams, Matthew Walker
Estimating the term…
A compound having the formula (I) R1-COOH. R1 is an alkyl or alkenyl group having a C7-11 backbone, optionally branched with a C1-6 alkyl group at any C position in the backbone, or a pharmaceutically acceptable salt, amide or ester thereof. The backbone of the alkyl or alkenyl group, and/or the branched alkyl groups, are optionally interrupted by one or more heteroatoms, provided that when R1 is an alkyl group having a C7 backbone, the branching does not consist only of a hexyl group at the α carbon of R1, or only of a methyl group at the γ carbon of R1, or of only single methyl groups at both the β and ω-1 carbons of R1, and provided that when R1 is an alkyl group having a C8 dor C11 backbone, the branching does not consist only of a propyl group at the α carbon of R1.
A method for treating or preventing a disease or a biomedical condition selected from seizure-related disorders, bipolar disorders, mania, depression, migraine, attention deficit hyperactivity disorders, latent HIV infection, Alzheimer's disease, chorea, schizophrenia, ischemia, cancer and fatal blood loss, the method comprising administering to a subject a therapeutically effective amount of at least one compound selected from the group consisting of nonanoic acid, 4-ethyloctanoic acid, 2-propyloctanoic acid, 2-butyloctanoic acid, 4-methylnonanoic acid, 8-methylnonanoic acid, 3-methylnonanoic acid, and 3-methylundecanoic acid.
Dependencies are inferred from the claim text.