Particle separation systems and methods

An apparatus for collecting a particle in a fluid sample, the apparatus comprising:

• an input channel;
• a detector configured to detect the particle in the input channel;
• a directional flow channel in fluid communication with the input channel;
• a valve configured to modulate fluid flow in the directional flow channel;
• an output channel in fluid communication with the input channel;
• a dispersion stage in fluid communication with the output channel;
• and
• a computer comprising a processor and a non-transitory memory with executable instructions stored thereon, which when executed by the processor cause the apparatus to:
• operate the detector to detect a first presence of the particle in a first aliquot of the sample;
• operate the valve to direct the flow of the first aliquot to a first volume to form a first isolated sample upon detecting the presence of the particle in the first aliquot;
• direct the first isolated sample to the dispersion stage to form a dispersed sample;
• and
• perform a separation procedure on the dispersed sample.