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US 2020/0206498 A1Published application
Devices for material delivery, electroporation, sonoporation, and/or monitoring electrophysiological activity
AssigneeNorthwestern University
InventorsRishi Arora, Alan Kadish, Jason Ng
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Abstract
The invention relates generally to systems and devices for material delivery, energy delivery, and/or monitoring electrophysiological activity, and method of use thereof. In particular, the present invention provides devices and systems, and methods of use thereof, configured to deliver therapeutic compositions, to provide electroporation and/or sonoporation to increase therapeutic efficiency, and to monitor electrophysiological activity, for example, before and after treatment.
Claims21
A device comprising:
- a) an elongate member with an inner lumen, wherein said inner lumen is configured for delivery of a therapeutic agent to a treatment site within a subject;
- b) an energy-delivery element, wherein said energy-delivery element is configured to deliver energy to said treatment site within a subject;
- and
- c) an electrophysiology monitoring element, wherein said electrophysiology monitoring element is configured to monitor electrical signals.
1 more element
A method of treating a disease or condition in a subject comprising:
- a) inserting a catheter into said subject and placing the distal end of said catheter at a treatment site;
- b) delivering a therapeutic agent to said treatment site through the lumen of said catheter;
- c) electroporating or sonoporating said treatment site with electrodes located on the distal end of said catheter.
(canceled)
Dependencies are inferred from the claim text.