Nasal aerosol delivery system

A method of delivering a treatment agent from a dose container to a subject using a nasal delivery device, the method comprising:

• inserting the dose container into a disposable drug cartridge that has a nasal prong with a mesh member at a distal end of the nasal prong, wherein the dose container includes a fluid delivery member comprising a flexible dose bulb and defining a fluid flow path from the flexible dose bulb to a distal end of the fluid delivery member,
• coupling the disposable drug cartridge to the nasal delivery device so that the mesh member is in contact with an ultrasonic actuator;
• applying pressure to the flexible dose bulb to break a storage seal separating the flexible dose bulb and from the fluid flow path;
• and
• delivering the treatment agent from the flexible dose bulb along the fluid flow path to the mesh member at a controlled rate.