Purified forms of rofecoxib, methods of manufacture and use
AssigneeTremeau Pharmaceuticals, Inc.
InventorsBradford C. SIPPY, Raymond SKWIERCZYNSKI, Jean-Marie SCHNEIDER, Simon H. DROUIN, Charles GUERIN
Life of this patent
Estimating the term…
Abstract
The subject matter disclosed herein relates to rofecoxib, also known as TRM-201 or RXB-201, its method of manufacture, and use. In certain aspects, the highly pure or substantially pure rofecoxib as provided herein has a favorable purity profile and is the active ingredient in a pharmaceutical composition that is administered to treat or prevent a number of conditions, including pain associated with a condition caused by a bleeding disorder.
Claims26
A pharmaceutical composition comprising highly pure rofecoxib or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier.
A pharmaceutical composition comprising 12.5 mg highly pure rofecoxib or an acceptable salt thereof and a pharmaceutically acceptable carrier.
A pharmaceutical composition comprising 17.5 mg highly pure rofecoxib or an acceptable salt thereof and a pharmaceutically acceptable carrier.
A pharmaceutical composition comprising 20 mg highly pure rofecoxib or an acceptable salt thereof and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.