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AssigneeOcera Therapeutics, Inc.
InventorsChristopher F. Rose, Marc-André Clément, Cristina R. Bosoi, Mariana Macedo Oliveira, Mélanie Tremblay, Chantal Bémeur
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Disclosed herein are methods of treating and preventing neuronal cell loss in a subject using ornithine in combination with phenylacetate or phenylbutyrate. In some embodiments, the subject has received or will receive a surgical procedure (for example, liver transplantation) for treating a liver disease. In some embodiments, the subject suffers from a liver disease and hypotension.
A method of treating a condition of neuron loss, comprising administering ornithine in combination with at least one of phenylacetate and phenylbutvrate to a subject in need thereof, and thereby relieving the condition, wherein the subject is a patient that had a liver disease and has experienced a traumatic bleeding.
A method of preventing a condition of neuron loss, comprising administering ornithine in combination with at least one of phenylacetate and phenylbutvrate to a subject in need thereof, and thereby preventing the condition, wherein the subject is a patient having a liver disease that is expected to experience a traumatic bleeding, a patient having a liver disease that is going to be treated by liver transplantation, or a patient suffering from hypotension.
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A method of treating a condition of neuron loss, comprising administering ornithine in combination with at least one of phenylacetate and phenylbutyrate to a subject in need thereof, and thereby relieving the condition, wherein the subject is a patient having a liver disease that has been treated by liver transplantation or a patient suffering from hypotension.
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Dependencies are inferred from the claim text.